🟢 New in Current Filing Our results of operations and financial condition may be adversely affected by risks associated with entering new lines of business, and our ability to execute our strategy. 🔒

🟢 New in Current Filing Consolidated Statements of Earnings 🔒

🟢 New in Current Filing Earnings per common share attributable to Cardinal Health, Inc. 🔒

🟢 New in Current Filing Total comprehensive income attributable to Cardinal Health, Inc. 🔒

🟢 New in Current Filing Vendor Reserves 🔒

🟢 New in Current Filing Income Taxes 🔒

🟢 New in Current Filing Variable Interest Entities 🔒

🟢 New in Current Filing Consolidated Variable Interest Entities 🔒

🟢 New in Current Filing GIA Share-Based Compensation 🔒

🟢 New in Current Filing Notes to Financial Statements 🔒

🟢 New in Current Filing Advanced Diabetes Supply Group ("ADS") 🔒

🟢 New in Current Filing GI Alliance ("GIA") 🔒

🟢 New in Current Filing Integrated Oncology Network ("ION") 🔒

🟢 New in Current Filing Specialty Networks 🔒

🟢 New in Current Filing Fair Value of Assets Acquired and Liabilities Assumed 🔒

🟢 New in Current Filing Notes to Financial Statements 🔒

🟢 New in Current Filing Opioid Lawsuits and Investigations 🔒

🟢 New in Current Filing Notes to Financial Statements 🔒

🟢 New in Current Filing Tax Effects of Goodwill Impairment Charges 🔒

🟢 New in Current Filing Fair Value of Financial Instruments 🔒

🟢 New in Current Filing Diluted earnings per common share attributable to Cardinal Health, Inc.: 🔒

🟢 New in Current Filing Segment Profit 🔒

🟢 New in Current Filing Restricted Share Units 🔒

🟢 New in Current Filing GIA Share-Based Compensation 🔒

🟢 New in Current Filing Vested at June 30, 2025 🔒

🟢 New in Current Filing Notes to Financial Statements 🔒

🟢 New in Current Filing Solaris Health 🔒

🟢 New in Current Filing Schedule II - Valuation and Qualifying Accounts 🔒

🟢 New in Current Filing Information About Our Executive Officers 🔒

🟢 New in Current Filing Directors and Corporate Governance 🔒

🟢 New in Current Filing Exhibits, Financial Statement Schedules 🔒

🟢 New in Current Filing Sudhakar Ramakrishna 🔒

🔴 No Match in Current Filing Changes to the U.S. healthcare environment may not be favorable to us. 🔒

🔴 No Match in Current Filing Our business could be affected by activist shareholders. 🔒

🔴 No Match in Current Filing Risk Factors 🔒

🔴 No Match in Current Filing Uncertain Tax Positions 🔒

🔴 No Match in Current Filing Consolidated Statements of Earnings/(Loss) 🔒

🔴 No Match in Current Filing Revision of Prior Period Consolidated Financial Statements 🔒

🔴 No Match in Current Filing Notes to Financial Statements 🔒

🔴 No Match in Current Filing As Reported 🔒

🔴 No Match in Current Filing Notes to Financial Statements 🔒

🔴 No Match in Current Filing Updated Segment Reporting Structure 🔒

🔴 No Match in Current Filing Investments 🔒

🔴 No Match in Current Filing Self-Insurance 🔒

🔴 No Match in Current Filing Notes to Financial Statements 🔒

🔴 No Match in Current Filing Total net assets acquired 🔒

🔴 No Match in Current Filing Notes to Financial Statements 🔒

🔴 No Match in Current Filing Opioid Lawsuits and Investigations 🔒

🔴 No Match in Current Filing Deferred Income Taxes 🔒

🔴 No Match in Current Filing Assets Measured on a Nonrecurring Basis 🔒

🔴 No Match in Current Filing Fair Value of Financial Instruments 🔒

🔴 No Match in Current Filing Segment Profit 🔒

🔴 No Match in Current Filing 16. Revision of Previously Issued Financial Statements (Unaudited) 🔒

🟡 Modified Concentrations of Credit Risk 🔒

🟡 Modified Opinion on the Financial Statements 🔒

🟡 Modified Net Investment Hedges 🔒

🟡 Modified Antitrust Litigation Proceeds 🔒

🟡 Modified Sales Returns and Allowances 🔒

🟡 Modified Risk Management and Strategy 🔒

🟡 Modified 12. Shareholders' Deficit 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Interest Rate, Currency, and Commodity Risk 🔒

🟡 Modified Fair Value Hedges 🔒

🟡 Modified Other Tax Matters 🔒

🟡 Modified Definition and Limitations of Internal Control Over Financial Reporting 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Revenue Recognition 🔒

🟡 Modified Accumulated Other Comprehensive Loss 🔒

🟡 Modified Identifiable net assets/(liabilities): 🔒

🟡 Modified Valuation of Goodwill 🔒

🟡 Modified Our business is subject to rigorous regulatory and licensing requirements. 🔒

🟡 Modified Other Financing Arrangements 🔒

🟡 Modified Risk Factors 🔒

🟡 Modified Loss Contingencies 🔒

🟡 Modified Other Civil Litigation 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified We could be subject to adverse changes in the tax laws or challenges to our tax positions. 🔒

🟡 Modified products and raw materials available to us and are subject to fluctuations in costs, availability, and regulatory risk associated with these products and raw materials. 🔒

🟡 Modified Noncontrolling Interests 🔒

🟡 Modified Our goodwill or other long-lived assets may be further impaired, which could require us to record additional significant charges to earnings in accordance with generally accepted accounting principles. 🔒

🟡 Modified Legal Proceedings 🔒

🟡 Modified Risk Factors 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified 10. Fair Value Measurements 🔒

🟡 Modified Assets Held for Sale 🔒

🟡 Modified Employee Retirement Savings Plans 🔒

🟡 Modified Economic (Non-Designated) Hedges 🔒

🟡 Modified Receivables and Allowance for Doubtful Accounts 🔒

🟡 Modified Unrecognized Tax Benefits 🔒

🟡 Modified Failure to effectively or efficiently complete or manage critical business processes could have unforeseen consequences. 🔒

🟡 Modified We could continue to suffer the adverse effects of competitive pressures, and changes in our relationships with significant customers could adversely affect us. 🔒

🟡 Modified Investments 🔒

🟡 Modified Consolidation in the U.S. healthcare industry may negatively impact our results of operations. 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified 13. Earnings Per Share Attributable to Cardinal Health, Inc. 🔒

🟡 Modified 11. Financial Instruments 🔒

🟡 Modified Our Pharmaceutical and Specialty Solutions segment’s profit margin could be adversely affected by changes in industry or market dynamics that we are not able to accurately predict. 🔒

🟡 Modified Our results of operations or strategic objectives could be adversely impacted if we fail to manage and complete divestitures. 🔒

🟡 Modified Total share-based compensation expense 🔒

🟡 Modified 7. Long-Term Obligations and Other Short-Term Borrowings 🔒

🟡 Modified Net deferred income tax liability 🔒

🟡 Modified Inventories 🔒

🟡 Modified Goodwill and Other Intangible Assets 🔒

🟡 Modified Consolidated Statements of Shareholders' Deficit 🔒

🟡 Modified Five Year Performance Graph 🔒

🟡 Modified Restructuring and Employee Severance 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Cash Flow Hedges 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Performance Share Units 🔒

🟡 Modified Opioid-related legal proceedings and the NOSA we have entered into could have additional or unexpected negative effects on our results of operations or business. 🔒

🟡 Modified Our sales and credit concentration is significant. 🔒

🟡 Modified Changes in Internal Control Over Financial Reporting 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Consolidated Statements of Comprehensive Income 🔒

🟡 Modified 14. Segment Information 🔒

🟡 Modified Product quality issues could adversely affect operations, profitability, cash flows, and our financial condition. 🔒

🟡 Modified Financial Statements and Supplementary Data 🔒

🟡 Modified Our business and results of operations could be adversely affected if we experience a material cyber-attack or other systems breach. 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Risk Factors 🔒

🟡 Modified Expected Volatility (3) 🔒

🟡 Modified Critical Audit Matter 🔒

🟡 Modified Recently Issued Financial Accounting Standards and Disclosure Rules Not Yet Adopted 🔒

🟡 Modified Risk Factors 🔒

🟡 Modified Consolidated Statements of Cash Flows 🔒

🟡 Modified 3. Divestitures 🔒

🟡 Modified Consolidated Balance Sheets 🔒

🟡 Modified Cardinal Health, Inc. Plan 🔒

🟡 Modified Our business is affected by events outside of our control including public health crises, extreme weather-related events and natural disasters, geopolitical, and other catastrophic events. 🔒

🟡 Modified Other Intangible Assets 🔒

🟡 Modified 5. Goodwill and Other Intangible Assets 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified 1. Basis of Presentation and Summary of Significant Accounting Policies 🔒

🟡 Modified Risk Factors 🔒

🟡 Modified Legal Proceedings 🔒

🟡 Modified Property and Equipment 🔒

🟡 Modified Cordis IVC Filter Matters 🔒

🟡 Modified 4. Restructuring and Employee Severance 🔒

🟡 Modified Recently Adopted Financial Accounting Standards. 🔒

🟡 Modified Effective Tax Rate 🔒

🟡 Modified Earnings before income taxes 🔒

🟡 Modified Balance at end of fiscal year 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Long-Term Debt 🔒

🟡 Modified Earnings before Income Taxes and Provision for Income Taxes 🔒

🟡 Modified Net earnings attributable to Cardinal Health, Inc. 🔒

🟡 Modified Commodity Price Risk Management 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified New York Opioid Stewardship Act 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Changes to the U.S. healthcare environment may not be favorable to us. 🔒

🟡 Modified Our ability to complete, integrate, and manage acquisitions could impact our strategic objectives and financial condition. 🔒

🟡 Modified Risk Factors 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Total net assets acquired 🔒

🟡 Modified Major Customers 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Risk Factors 🔒

🟡 Modified Notes to Financial Statements 🔒

🟡 Modified Our business and operations depend on the proper functioning of information systems, critical facilities, and distribution networks and could be negatively impacted by events outside of our control. 🔒

🟡 Modified Changes or uncertainty in U.S. or international trade policies and exposure to economic, political and currency, and other risks could disrupt our global operations or negatively impact our financial results. 🔒

🟡 Modified Business Combinations 🔒

🟡 Modified Amortization and Other Acquisition-Related Costs 🔒

🟡 Modified Deferred Income Taxes 🔒

🟡 Modified PeriodTotal Numberof SharesPurchased (1)Average Price Paid per ShareTotal Number of SharesPurchasedas Part of Publicly Announced Programs (2)ApproximateDollar Value ofShares That MayYet be PurchasedUnder the Programs (2)(in millions)April 20257 $133.13 — $2,743 May 20256 150.62 — 2,743 June 20257 158.38 — 2,743 Total20 $147.17 — $2,743 🔒

Cardinal Health Inc.: 10-K Risk Factor Changes

The outcome or resolution of certain legal proceedings could adversely impact our cash flows or results of operations.