🟢 New in Current Filing REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM 🔒

🟢 New in Current Filing (In millions) 🔒

🟢 New in Current Filing Accounting Pronouncements Pending Adoption 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing Cash Equivalents 🔒

🟢 New in Current Filing Business Combinations 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing Restructuring 🔒

🟢 New in Current Filing 2023 Impairment of Goodwill 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing Liability- Classified RSU 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing 0.78% - 5.54% 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing Restructuring 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing Employee Separation Costs (1) 🔒

🟢 New in Current Filing Other (Expense) Income, Net 🔒

🟢 New in Current Filing 8. LEGAL PROCEEDINGS 🔒

🟢 New in Current Filing Acquisition of GRAIL 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing SEC Inquiry Letter 🔒

🟢 New in Current Filing Derivative and Class Action Complaint 🔒

🟢 New in Current Filing Securities Class Actions 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing DOJ Civil Investigative Demand 🔒

🟢 New in Current Filing BGI Genomics Co. Ltd. and its Affiliates 🔒

🟢 New in Current Filing 9. INCOME TAXES 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing Retirement Plan 🔒

🟢 New in Current Filing Deferred Compensation Plan 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing Reportable Segment Information 🔒

🟢 New in Current Filing Core Illumina: 🔒

🟢 New in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟢 New in Current Filing Geographic Data 🔒

🟢 New in Current Filing CONTROLS AND PROCEDURES 🔒

🟢 New in Current Filing MANAGEMENT’S REPORT ON INTERNAL CONTROL OVER FINANCIAL REPORTING 🔒

🟢 New in Current Filing Opinion on Internal Control Over Financial Reporting 🔒

🟢 New in Current Filing Basis for Opinion 🔒

🟢 New in Current Filing Definition and Limitations of Internal Control Over Financial Reporting 🔒

🟢 New in Current Filing ADOPTIONS, MODIFICATIONS OR TERMINATIONS OF TRADING PLANS 🔒

🟢 New in Current Filing DIRECTORS, EXECUTIVE OFFICERS, AND CORPORATE GOVERNANCE 🔒

🟢 New in Current Filing Executive Officers 🔒

🟢 New in Current Filing Section 16(a) of the Exchange Act 🔒

🟢 New in Current Filing Audit Committee Financial Expert 🔒

🟢 New in Current Filing Code of Conduct 🔒

🟢 New in Current Filing EXECUTIVE COMPENSATION 🔒

🟢 New in Current Filing SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS 🔒

🟢 New in Current Filing CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE 🔒

🟢 New in Current Filing PRINCIPAL ACCOUNTANT FEES AND SERVICES 🔒

🟢 New in Current Filing EXHIBITS, FINANCIAL STATEMENT SCHEDULES 🔒

🟢 New in Current Filing Financial Statements 🔒

🟢 New in Current Filing Financial Statement Schedules 🔒

🟢 New in Current Filing Index to Exhibits 🔒

🔴 No Match in Current Filing We currently are prohibited from integrating GRAIL’s business, and if such integration is ultimately permitted, we may not be able to integrate GRAIL’s business successfully or manage the combined business effectively. Many of the anticipated synergies and other benefits of acquiring GRAIL may not be realized or may not be realized within the expected time frame. 🔒

🔴 No Match in Current Filing Adoption of ASU No. 2020-06 🔒

🔴 No Match in Current Filing Accounting Pronouncements Adopted in 2020 🔒

🔴 No Match in Current Filing Revenue Recognition 🔒

🔴 No Match in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🔴 No Match in Current Filing Cash Equivalents and Debt Securities 🔒

🔴 No Match in Current Filing Property and Equipment 🔒

🔴 No Match in Current Filing Goodwill, Intangible Assets and Other Long-Lived Assets 🔒

🔴 No Match in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🔴 No Match in Current Filing Acquisition of GRAIL, Inc. 🔒

🔴 No Match in Current Filing Unaudited Pro Forma Financial Information 🔒

🔴 No Match in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🔴 No Match in Current Filing 0% Convertible Senior Notes due 2023 (2023 Convertible Notes) 🔒

🔴 No Match in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🔴 No Match in Current Filing 0.06% - 2.98% 🔒

🔴 No Match in Current Filing 0.5 - 1.0 year 🔒

🔴 No Match in Current Filing NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟡 Modified Advertising Costs 🔒

🟡 Modified Income Taxes 🔒

🟡 Modified Intangible Assets and Other Long-Lived Assets — Impairment Assessment 🔒

🟡 Modified Opinion on the Financial Statements 🔒

🟡 Modified Our operating results may vary significantly from period to period. 🔒

🟡 Modified Credit Agreement 🔒

🟡 Modified Use of Estimates 🔒

🟡 Modified Research and Development 🔒

🟡 Modified NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟡 Modified Business Overview 🔒

🟡 Modified We are subject to various uncertainties and restrictions while the Acquisition remains subject to ongoing regulatory and legal review and proceedings related thereto, including the EC Divestment Decision, that could adversely affect our business, financial condition and results of operations. 🔒

🟡 Modified Non-Marketable Equity Securities 🔒

🟡 Modified Summary of Term Debt Obligations 🔒

🟡 Modified Sales of Unregistered Securities 🔒

🟡 Modified Our acquisitions expose us to risks that could adversely affect our business, and we may not achieve the anticipated benefits of acquisitions of businesses or technologies. 🔒

🟡 Modified Derivative Financial Instruments 🔒

🟡 Modified 6. STOCKHOLDERS’ EQUITY 🔒

🟡 Modified RECENT ACCOUNTING PRONOUNCEMENTS 🔒

🟡 Modified Cash Flow Summary 🔒

🟡 Modified LIQUIDITY AND CAPITAL RESOURCES 🔒

🟡 Modified Goodwill, Intangible Assets and Other Long-Lived Assets 🔒

🟡 Modified 2022 Impairment of Goodwill 🔒

🟡 Modified NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟡 Modified Venture Funds 🔒

🟡 Modified Contract Assets and Liabilities 🔒

🟡 Modified The armed conflict between Russia and Ukraine, the international sanctions imposed on Russia, and the restrictions imposed on exports to Russia will likely continue to negatively affect our business. Armed conflict in the Middle East or elsewhere could also negatively impact us. 🔒

🟡 Modified NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟡 Modified Share Repurchases 🔒

🟡 Modified Nasdaq Biotechnology Index, and S&P 500 Index 🔒

🟡 Modified Fiscal Year 🔒

🟡 Modified About Illumina 🔒

🟡 Modified Revenue Recognition 🔒

🟡 Modified Stock Options 🔒

🟡 Modified Property and Equipment 🔒

🟡 Modified (Loss) Earnings per Share 🔒

🟡 Modified Restricted Stock 🔒

🟡 Modified Share-Based Compensation 🔒

🟡 Modified Contingent Consideration Liabilities 🔒

🟡 Modified Stock Units 🔒

🟡 Modified Financial Overview 🔒

🟡 Modified Provision for Income Taxes 🔒

🟡 Modified We are unable to predict the extent to which public health crises, such as the COVID-19 pandemic, may adversely impact our business operations and financial performance. 🔒

🟡 Modified MARKET INFORMATION 🔒

🟡 Modified Other Liability-Classified Awards 🔒

🟡 Modified NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟡 Modified (In millions, except par value) 🔒

🟡 Modified Acquisition of GRAIL, Inc. 🔒

🟡 Modified Property and Equipment 🔒

🟡 Modified Helix Contingent Value Right 🔒

🟡 Modified NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟡 Modified (In millions) 🔒

🟡 Modified CONSOLIDATED FINANCIAL STATEMENTS 🔒

🟡 Modified Accrued Liabilities 🔒

🟡 Modified (Accumulated 🔒

🟡 Modified NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟡 Modified Fair Value Measurements 🔒

🟡 Modified (In millions, except per share amounts) 🔒

🟡 Modified Gross Margin 🔒

🟡 Modified RESULTS OF OPERATIONS 🔒

🟡 Modified Other Income (Expense) 🔒

🟡 Modified 0% Convertible Senior Notes due 2023 (2023 Convertible Notes) 🔒

🟡 Modified NOTES TO CONSOLIDATED FINANCIAL STATEMENTS — (Continued) 🔒

🟡 Modified Revenue by Geographic Area 🔒

🟡 Modified Operating Expense 🔒

🟡 Modified Accounts Receivable 🔒

🟡 Modified Share-Based Compensation 🔒